Search on: PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE 
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Descriptor English:   Pyruvate Dehydrogenase (Lipoamide)-Phosphatase 
Descriptor Spanish:   Piruvato Deshidrogenasa (Lipoamida)-Fosfatasa 
Descriptor Portuguese:   Piruvato Desidrogenase (Lipoamida)-Fosfatase 
Synonyms English:   PDH Phosphatase
Phosphatase, PDH
Phosphatase, Pyruvate Dehydrogenase
Pyruvate Dehydrogenase Phosphatase
Pyruvate Dehydrogenase Phosphate Phosphatase  
Tree Number:   D08.811.277.352.650.625.725
Definition English:   (Pyruvate dehydrogenase (lipoamide))-phosphate phosphohydrolase. A mitochondrial enzyme that catalyzes the hydrolytic removal of a phosphate on a specific seryl hydroxyl group of pyruvate dehydrogenase, reactivating the enzyme complex. EC 3.1.3.43. 
History Note English:   94; was PYRUVATE DEHYDROGENASE PHOSPHATASE 1975-93 (see under PHOSPHOPROTEIN PHOSPHATASES 1979-90, see under PHOSPHOMONOESTERASES 1975-78) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   31902 
Unique Identifier:   D011769 

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